The trial protocol was prospectively registered on the Australian New Zealand Clinical Trials Registry ( ACTRN 12613000822785) on. Alternative fitness training protocols may need to be explored. A definitive adequately-powered randomised trial is required. Moderate-intensity fitness training was safe but achievement of target duration and intensity was challenging for stroke survivors. Although there were no significant between-group differences, this feasibility trial was not powered to detect change. Significant improvements in VO 2 peak in both groups were observed ( p < 0.05). Baseline peak oxygen uptake (VO 2) levels were low (15.94 ml/kg/min). Progression of duration and intensity was limited mean of 10 sessions to achieve target duration (30 min). The median (% IQR) supervised sessions was 19.5 (81% 12, 20) and 20 (83% 19, 22) in the intervention and control groups, respectively. Twenty participants (10 intervention, 10 control) were recruited. Resultsįeasibility: Seventy-one (50%) of 141 screened participants were eligible (29% did not agree to participate). Outcome measures included adverse events, peak oxygen uptake (VO 2), functional exercise capacity (6-Minute Walk Test, 10-m Walk Test) and health-related quality of life (Short Form-36) and mood (Patient Health Questionnaire, PHQ9). Moderate-intensity fitness training or control (low-intensity) exercise was offered biweekly for 12 weeks. Eligibility criteria included ambulant (> 100 m), 6 weeks-12 months post stroke.
MethodsĪ pilot, prospective, patient- and assessor-blinded randomised controlled trial conducted in a tertiary, metropolitan hospital-based community rehabilitation centre. The aim was to determine the safety and feasibility of moderate-intensity cardiovascular training following stroke, including measurement of adherence to training.
While cardiovascular training seems an empirically appropriate intervention, the optimal dosage and intensity of cardiovascular training in stroke survivors remains unclear.
Stroke is a leading cause of disability worldwide and the cardiovascular fitness levels of stroke survivors are diminished to an extent that impairs functioning and activities of daily living performance.
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